Protein encapsulation within synthetic molecular hosts

Molecular Encapsulation within an Engineered Protein Cage for Drug Delivery

F a c u l t y M e n t o r

IP encapsulation within IP

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Synthetic hosts via molecular imprinting--are universal synthetic antibodies realistically possible?

Of the many ways to make synthetic hosts, one of the most appealing involves molecular imprinting. In the commonest approach monomer units assemble around or are attached to a template (imprint) molecule and then linked together using a cross-linking agent. Template removal ideally leaves cavities within the molecularly imprinted polymer (MIP) that possess a shape and functional group complemen...

Silk micrococoons for protein stabilisation and molecular encapsulation

Naturally spun silks generate fibres with unique properties, including strength, elasticity and biocompatibility. Here we describe a microfluidics-based strategy to spin liquid native silk, obtained directly from the silk gland of Bombyx mori silkworms, into micron-scale capsules with controllable geometry and variable levels of intermolecular β-sheet content in their protein shells. We demonst...

Nanoporous hosts for the encapsulation of conductive nanostructured materials